Infectious Diseases and Microbiology - Ascaris lumbricoides Infection ( Ascaris Lumbricoides)1/25/2024 Infectious Diseases and Microbiology - Ascaris lumbricoides Infection ( Ascaris Lumbricoides) Lumbricoides Ascaris Lumbricoides largest roundworms in the human intestine, known as nematodes.the most prevalent nematode infection in the world. A lumbricoides can grow to a length of 20 to 35 centimeters. The method of transmission is via eating eggs that have been infected by human waste in the soil. After several weeks of soil incubation, eggs begin to develop into embryos. The worm load or burden affects how severe the symptoms are. One of the symptoms that arises from the larvae migrating to the lungs is acute transitory pneumonitis. Large worm burdens in the colon can cause malnutrition and bowel blockages. Adult worm migration can cause peritonitis related to intestinal perforation, duct obstructions, and appendix occlusion. After hatching in the small intestine, larvae pass through the mucosa and are passively carried by portal blood to the liver and then the lungs. Both pneumonitis and eosinophilia are brought on by the lung migration. The larvae enter the lung through alveoli, where they are then coughed up and consumed. The mature worm stays in the digestive tract, where it deposits eggs that are expelled through the stool. Instead of attaching, they remain in their current location by moving constantly. The worms migrate and settle in ducts when the human host becomes feverish or receives antibiotic treatment, which may restrict the flow of blood. Usually, the diagnosis is made based on the presence of adult or egg worms in the feces. The outer surface of the oval-shaped eggs is knobby. Sputum samples taken during the lung migration can show eosinophils and larvae. Mebendazole or pyrantel pamoate are the forms of treatment. Preventive hygiene and appropriate disposal of human waste are essential components of prevention.
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