​Pharmacology - Scopolamine

​Pharmacology - Scopolamine 
The drug Scopolamine 
The antiemetic. In addition, behaviors that are consistent with the antagonistic effect on the parasympathetic nervous system

Method of Operation 
Muscarinic receptors will be subjected to reversible competitive antagonism. The blockage of receptors in the vestibular nucleus and in the vomiting center is responsible for the antiemetic effects.

Orally active (half life of five hours). It is especially effective to apply a transdermal patch behind the ear, and its effects might last for up to three days.

Use in Clinical Settings
The anti-motion sickness medication is most effective when administered as a preventative measure. There is no successful treatment for chemotherapy-induced vomiting that is mediated by the CTZ. It is effective against the local stimulation in the stomach.

Unfavorable Effects
Drowsiness is present. Insomnia can occur. Dry mouth, tachycardia, impaired vision, and urine retention are some of the possible side effects that can be attributed to muscarinic receptor inhibition. In cases of closed-angle glaucoma, avoid.