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​Symptoms and Signs – Differential Diagnosis of Leprosy
• Carpal tunnel syndrome
• Cutaneous leishmaniasis
• Fungal infections
• Lymphomatoid granulomatosis
• Rheumatoid arthritis
• Sarcoidosis
• Systemic lupus erythematosus
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​Symptoms and Signs – Differential Diagnosis of Leptomeningeal Lesions
• Bacterial or viral meningitis
• Fungal infections (e.g., Cryptococcus)
• Histiocytosis
• Lyme disease
• Metastases
• Multiple sclerosis
• Neurocysticercosis
• Rheumatoid nodules
• Sarcoidosis
• Tuberculosis
• Vasculitis
• Wegener’s granulomatosis
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​Symptoms and Signs – Differential Diagnosis of Leukocoria
• Cataract
• Familial exudative vitreoretinopathy
• Retinal detachment
• Retinal telangiectasia
• Retinoblastoma
• Retrolenticular vascularized membrane
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​Symptoms and  Signs – Differential Diagnosis of  Korsakoff’s Psychosis
• Stroke affecting the temporal lobes or hippocampus
• Trauma affecting the temporal lobes or hippocampus
• Tumor affecting the temporal lobes or hippocampus
• Cerebral anoxia
• Transient global amnesia
• Dementing illness
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​Symptoms and  Signs – Differential Diagnosis of  Labyrinthitis
• Acute labyrinthine ischemia (vascular insufficiency)
• Benign positional vertigo
• Cholesteatoma
• Drug induced
• Eighth nerve tumor
• Head trauma
• Labyrinthine fistula
• Meniere’s disease
• Other forms of labyrinthitis (bacterial and syphilitic)
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​Symptoms and Signs – Differential Diagnosis of  Lactose Intolerance
• Bowel neoplasm
• Celiac disease
• Cystic fibrosis
• Diverticular disease
• Inflammatory bowel disease (IBD)
• Irritable bowel syndrome (IBS)
• Laxative abuse
• Nontropical and tropical sprue
• Pancreatic insufficiency
• Parasitic disease (e.g., giardiasis)
• Viral or bacterial infections
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​Symptoms and Signs – Differential Diagnosis of Laryngeal Cancer
• Allergic and nonallergic rhinosinusitis
• Gastroesophageal reflux
• Laryngeal papilloma
• Laryngitis
• Tracheomalacia
• Vocal cord paralysis secondary to a neurologic condition or secondary to entrapment of the recurrent laryngeal nerve caused by mediastinal compression
• Voice abuse leading to hoarseness
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​Symptoms and Signs – Differential Diagnosis of Laryngitis
YOUNG CHILDREN WITH SIGNS OF AIRWAY
OBSTRUCTION
• Supraglottitis (epiglottitis)
• Laryngotracheobronchitis
• Tracheitis
• Foreign body aspiration
ADULTS WITH PERSISTENT HOARSENESS
• Allergic and nonallergic rhinosinusitis
• Gastroesophageal reflux
• Voice abuse leading to hoarseness
• Laryngeal papilloma
• Laryngeal carcinoma
• Vocal cord paralysis secondary to a neurologic condition or
secondary to entrapment of the recurrent laryngeal nerve caused
by mediastinal compression
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