nDermatology - Agiosarcoma
An very unusual and malignant growth of endothelial cells is called angiosarcoma. Purpuric macules, papules, brilliant red or violaceous nodules, and even black or solid nodules that bleed readily and ulcerate are examples of lesions. Normal skin typically has lesions on the scalp and upper forehead, or there may be localized lymphedema, such as post-irradiation lymphedema or Stuart-Treves syndrome after a mastectomy. Clinical diagnosis is made, and a biopsy confirms the diagnosis. Other vascular lesions, lymphoma, pyogenic granuloma, and Kaposi sarcoma are among the differential diagnoses. Treatment consists of wide-margin excision and chemotherapy (paclitaxel or liposomal doxorubicin); nonetheless, the 5-year survival rate is still somewhat higher than 10% even with treatment.
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