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MEDICINE 

​Dermatology - Grover Disease

2/3/2024

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​Dermatology - Grover Disease 
Grover's disease
Grover's illness is a skin condition characterized by itching and resembling Darier's disease. However, it does not have a known genetic propensity and is typically temporary. Adult onset often occurs around the age of 50, with a higher prevalence in men compared to women. Precipitating factors encompass intense physical exertion that induces sweating, exposure to sun radiation, high temperatures, prolonged fever, and individuals confined to bed. Alternative term: transitory acantholytic dermatosis.The primary symptom is pruritus.
Abnormalities
The individual has developed distinct papular or papulovesicular lesions, which might range from few to many in number. When touched, the surface might feel either smooth or warty.
The diagnosis is made based on clinical observations, and the possible conditions to consider are eczema, folliculitis, solar lentigo, solar keratosis, scabies, miliaria, Darier disease, Hailey-Hailey disease, and pemphigus vulgaris.
The recommended treatment involves the use of glucocorticosteroids applied under occlusion, as well as UVB or PUVA photochemotherapy.
Administer oral glucocorticosteroids, dapsone, and isotretinoin to patients who do not respond to other treatments.
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