Dermatology - Harlequin Fetus

Dermatology - Harlequin Fetus 
The harlequin fetus is a very uncommon ichthyosis characterized by an uncommon fibrous protein in the epidermis.
The infant is born with extremely thick stratum corneum plates that are divided by large fissures and fractures. Although there have been cases of these newborns surviving for weeks or even months after delivery, most of them pass away soon after. An ugly look is caused by skin infection and missing or deformed ears.
Clinical diagnosis is made.
It is best to keep newborns in an incubator with water saturating the air. For a while, careful temperature monitoring, parenteral fluid replacement, and nutrient replenishment may be required.