Dermatology - Hereditary Angioedema

Dermatology - Hereditary Angioedema 
a dangerous autosomal dominant condition that could develop after emotional or physical trauma.
Rarely does urticaria occur. The patient presents with acute stomach pain due to angioedema of the intestinal wall, laryngeal edema episodes, and angioedema of the face and limbs.
Subcutaneous edema that results in severe deformity if it affects the face.
The complement system is involved in anomalies in the laboratory: low C4 value in the presence of normal C1 and C3 levels, and decreased levels of C1-esterase inhibitor (85%) or malfunctioning inhibitor (15%). Bradykinin development causes angioedema because the main inhibitor of kallikrein and Hageman factor—two enzymes necessary for kinin generation—is C1-esterase inhibitor. Events may pose a hazard to life.
Stanazolol or Danazol. prolonged treatment. Be on the lookout for irregular menses and hirsutism.
Whole fresh plasma or a C1-esterase inhibitor in an acute episode. Icatibant is an extremely potent bradykinin-B2-receptor antagonist that can be used subcutaneously.