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Differential Diagnosis of Anovulation • Weight loss/malnutrition • Thyroid dysfunction (hypothyroidism, hyperthyroidism) • Systemic diseases (e.g., liver disease) • Strenuous exercise • Polycystic ovary syndrome • Pituitary disorders (infarction, infection, trauma, irradiation, surgery, microadenomas, macroadenomas) • Isolated gonadotropin deficiency • Idiopathic hypopituitarism • Empty sella syndrome • Drug induced • Anorexia and bulimia • Adrenal hyperfunction (Cushing’s syndrome, congenital adrenal hyperplasia) 
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