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Differential Diagnosis of Drug Induced Anemia
• Drugs that may produce or promote blood loss: aspirin, alcohol, nonsteroidal anti-inflammatory agents, corticosteroids, anticoagulants
• Drugs that may interfere with red cell production by inducing marrow suppression or aplasia: alcohol, antineoplastic drugs, antithyroid drugs, antibiotics, oral hypoglycemic agents, phenylbutazone, azidothymidine (AZT)
• Drugs that interfere with vitamin B12, folate, or iron absorption or utilization: nitrous oxide, anticonvulsant drugs, antineoplastic drugs, isoniazid, cycloserine
• Drugs capable of promoting hemolysis: immune mediated, penicillins, quinine, methyldopa, procainamide, mitomycin C, oxidative stress, antimalarials, sulfonamide drugs, nalidixic acid
• Drugs that may produce or promote blood loss: aspirin, alcohol, nonsteroidal anti-inflammatory agents, corticosteroids, anticoagulants
• Drugs that may interfere with red cell production by inducing marrow suppression or aplasia: alcohol, antineoplastic drugs, antithyroid drugs, antibiotics, oral hypoglycemic agents, phenylbutazone, azidothymidine (AZT)
• Drugs that interfere with vitamin B12, folate, or iron absorption or utilization: nitrous oxide, anticonvulsant drugs, antineoplastic drugs, isoniazid, cycloserine
• Drugs capable of promoting hemolysis: immune mediated, penicillins, quinine, methyldopa, procainamide, mitomycin C, oxidative stress, antimalarials, sulfonamide drugs, nalidixic acid
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