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​Differential Diagnosis of Lactic Acidosis 
• Streptozocin
• Shock (hypovolemic, cardiogenic, endotoxic)
• Severe congestive heart failure (CHF)
• Severe anemia
• Sepsis
• Seizure activity
• Salicylates
• Respiratory failure (asphyxia)
• Nucleoside reverse transcriptase inhibitors (e.g., zidovudine, didanosine, stavudine)
• Neoplastic diseases (e.g., leukemia, lymphoma)
• Liver or renal failure
• Isoniazid
• HIV infection
• Glucose-6-phosphate dehydrogenase (G6PD) deficiency and others
• Fructose or sorbitol
• Ethanol, methanol, ethylene glycol
• Diabetes mellitus (DM)
• Carbon monoxide (CO) or cyanide poisoning
• Biguanides (phenformin, metformin [usually occurring in patients with renal insufficiency])
• Alkalosis
• Abnormal intestinal flora
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Kembara Xtra 

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