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Differential Diagnosis of Low Reticulocyte Count Anemia
• Microcytic anemia (mean corpuscular volume [MCV] < 80): iron deficiency, thalassemia minor, sideroblastic anemia, lead poisoning
• Macrocytic anemia (MCV > 100): megaloblastic anemias, folate deficiency, vitamin B12 deficiency, drug-induced megaloblastic anemia, nonmegaloblastic macrocytosis, liver disease,
hypothyroidism
• Normocytic anemia (MCV 80–100): early iron deficiency, aplastic anemia, myelophthisic disorders, endocrinopathies, anemia of chronic disease, uremia, mixed nutritional deficiency
• Microcytic anemia (mean corpuscular volume [MCV] < 80): iron deficiency, thalassemia minor, sideroblastic anemia, lead poisoning
• Macrocytic anemia (MCV > 100): megaloblastic anemias, folate deficiency, vitamin B12 deficiency, drug-induced megaloblastic anemia, nonmegaloblastic macrocytosis, liver disease,
hypothyroidism
• Normocytic anemia (MCV 80–100): early iron deficiency, aplastic anemia, myelophthisic disorders, endocrinopathies, anemia of chronic disease, uremia, mixed nutritional deficiency
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