​Infectious Diseases and Microbiology - Meningitis in a Child ( Haemophilus Influenza)A Child with Meningitis

​Infectious Diseases and Microbiology - Meningitis in a Child ( Haemophilus Influenza)
A Child with Meningitis

The flu virus Haemophilus
There are six types of Gram-negative coccobacilli. They need X (heme) and V (NAD) factors to grow.

The polysaccharide capsule is the basis for six serotypes. 

Sporadic outbreaks happen when people come into close contact with respiratory secretions that contain encapsulated serotypes. Pathogens most often come in type b.

Either pneumonia or meningitis are the most dangerous symptoms. You can get pharyngitis, epiglottitis, sinusitis, otitis media, abscesses, septic arthritis, and conjunctivitis from H. influenzae type b. When young children get meningitis, they are more likely to have neurological problems that can range from losing their hearing to having serious mental retardation.

The antiphagocytic capsule, endotoxin, an IgA protease, and attaching pili are some of the factors that make a virus strong. For immune clearance to happen, protective antibodies must bind to the capsule and make opsonization easier. The main pathogenic mechanism is the host's inflammatory reaction.

With an immune latex diagnosis agglutination test, H influenzae type b can be found directly in cerebrospinal fluid. Culture needs X and V factors, which can be found in chocolate agar.
 

Some antibiotics, like ampicillin and third-generation cephalosporins, need to be tested for resistance before they can be used. Chemoprophylaxis with rifampin is sometimes given to family members who have been exposed.
Vaccinating kids with a conjugated pure type b capsular polysaccharide is one way to stop it.