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MEDICINE 

Infectious Diseases and Microbiology - ​Sexually transmitted nongonococcal urethritis caused by Chlamydia trachomatis

1/18/2024

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Infectious Diseases and Microbiology - ​Sexually transmitted nongonococcal urethritis caused by Chlamydia trachomatis
Chlamydia trachomatis missing a normal peptidoglycan, resembling a gram-negative cell wall and known as  obligatory parasite inside cells.
The infectious external form is called the elementary body, while the metabolically active intracellular form is called the reticulate body.

Direct contact is the basis for transmission. The most prevalent bacterial sexually transmitted illness in the US is called C trachomatis. several serovars linked to infections of the vaginal and ocular tracts.
Numerous illnesses, such as trachoma, inclusion conjunctivitis, newborn pneumonia, nongonococcal urethritis, Reiter syndrome, lymphogranuloma venereum, and pelvic inflammatory disease, are caused by clinical C trachomatis. 

An infected birth canal can cause infection in newborns. Both flies and fingers can directly spread ocular infections.

The primary pathogenic mechanism is tissue damage resulting from the inflammatory response of the host. Depending on the infection site, recurrent infections might result in blindness and infertility due to progressive inflammation and tissue damage. Conjunctivitis in infants may be followed by corneal scarring.

 Diagnosis is accomplished by the use of nucleic acid amplification assays, cell culture, and direct fluorescence assays.
Assessment, Management, and Antibiotics such as tetracyclines, macrolides, and fluroquinolones can be used to treat C trachomatis, depending on the clinical presentation. Safe sexual behavior, quick infection treatment, and preventing reinfection are all part of prevention. Hygiene and face cleaning are crucial in the fight against trachoma.
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