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KembaraXtra - Medical Terms - acute tubular necrosis (ATN)
Acute tubular necrosis (ATN) is a condition involving damage to the kidney tubules, usually caused by reduced blood supply (ischaemia) or exposure to toxic substances. This damage disrupts normal kidney function, particularly the ability to filter waste and regulate fluid balance.
Early in the condition, the kidneys may produce urine that is neither concentrated nor diluted (isosthenuria), even when urine output is still relatively high. As the condition progresses, the glomerular filtration rate decreases, often leading to oliguria, or reduced urine output. Dialysis may be required to support the patient during recovery. If the underlying cause is treated, kidney function often recovers within several weeks.
Acute tubular necrosis (ATN) is a condition involving damage to the kidney tubules, usually caused by reduced blood supply (ischaemia) or exposure to toxic substances. This damage disrupts normal kidney function, particularly the ability to filter waste and regulate fluid balance.
Early in the condition, the kidneys may produce urine that is neither concentrated nor diluted (isosthenuria), even when urine output is still relatively high. As the condition progresses, the glomerular filtration rate decreases, often leading to oliguria, or reduced urine output. Dialysis may be required to support the patient during recovery. If the underlying cause is treated, kidney function often recovers within several weeks.
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