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Orthopaedic Surgery - Wrist Pain
Basics
Wrist pain is a common clinical complaint with many possible causes, including:
Trauma
Overuse
Degenerative disease
Inflammatory disease
Infection
and
Neurologic disorders.
A detailed history and focused physical examination are essential for establishing the:
Correct diagnosis
and selecting appropriate:
Treatment.
History
Important historical features include:
Onset
Duration
Frequency
and
Exact location of pain.
Additional symptoms should be documented, including:
Swelling
Erythema
Clicking or snapping
Loss of motion
Numbness or tingling
Weakness
and relationship to:
Specific activities.
General Medical History
Ask about conditions that may contribute to wrist disease, including:
Rheumatoid arthritis
Osteoarthritis
Gout
Diabetes
Immunosuppression
and previous:
Infection or trauma.
Classification
Wrist pain can broadly be classified as:
Traumatic
Inflammatory
Degenerative
Infectious
or
Neurologic.
Common Causes
Frequent causes include:
Fracture
Fracture nonunion
Arthritis
Tendinitis or tendinopathy
and
Ligament injury.
Epidemiology
Wrist pain is particularly common among:
Athletes
and individuals involved in repetitive:
Upper-extremity activity.
Athletes
Historical studies have reported wrist pain in approximately:
32–73% of young athletes
depending on the sport and population studied.
Emergency Department Visits
In the United States, wrist injuries have historically accounted for approximately:
2.5% of emergency department visits.
Pregnancy Considerations
Pregnant patients with wrist discomfort accompanied by:
Numbness
or
Tingling
should be evaluated for:
Carpal tunnel syndrome.
Fluid retention during pregnancy can increase pressure within the:
Carpal tunnel.
Associated Conditions
Systemic disorders associated with wrist pain include:
Rheumatoid arthritis
Osteoarthritis
Gout
and
Infection.
Diagnostic Approach
The location of pain is highly useful for narrowing the:
Differential diagnosis.
Wrist pain can be categorized anatomically as:
Radial-sided
Dorsal
Ulnar-sided
Volar or palmar
or
Diffuse.
Radial-Sided Wrist Pain
Important causes include:
de Quervain tenosynovitis
Intersection syndrome
Scaphoid fracture
Scapholunate ligament injury
Wartenberg syndrome
and
Thumb CMC or STT arthritis.
de Quervain Tenosynovitis
de Quervain disease is a stenosing tenosynovitis involving the:
First dorsal compartment.
The affected tendons are:
Abductor pollicis longus
and
Extensor pollicis brevis.
Typical History
Patients often report repetitive:
Thumb
or
Wrist activity.
Pain is localized near the:
Radial styloid.
Eichhoff / Finkelstein-Type Maneuver
With the thumb flexed into the palm and the wrist moved into:
Ulnar deviation
sharp pain over the first dorsal compartment supports the diagnosis.
The commonly performed thumb-in-fist maneuver is more accurately termed the:
Eichhoff test.
Alternative Provocative Testing
Wrist hyperflexion combined with thumb abduction may also reproduce:
First-compartment pain.
Intersection Syndrome
Intersection syndrome is an overuse disorder occurring where the:
First dorsal compartment tendons
cross the:
Second dorsal compartment tendons.
Location
Pain is typically located approximately:
4 cm proximal to the dorsal wrist.
Cause
It is usually associated with repetitive:
Wrist extension
and
Forearm motion.
Scaphoid Fracture
Patients typically report trauma, especially:
A fall on an outstretched hand.
Examination
Suggestive findings include tenderness at the:
Anatomic snuffbox
Scaphoid tubercle
and pain with:
Axial compression of the thumb ray.
Active thumb motion may also produce:
Pain.
Scapholunate Ligament Injury
Scapholunate ligament injury can produce:
Radial-dorsal wrist pain
and
Mechanical instability.
Watson Test
The:
Scaphoid shift or Watson test
is used to assess:
Scapholunate instability.
Pain, abnormal scaphoid translation, or a reproducible:
Clunk
may support the diagnosis.
Definitive Diagnosis
When uncertainty remains, wrist:
Arthroscopy
remains the most definitive method of directly evaluating the:
Scapholunate ligament.
Wartenberg Syndrome
Wartenberg syndrome results from irritation of the:
Superficial radial sensory nerve.
Cause
Mechanical compression can occur from:
Watches
Bracelets
or other constrictive objects.
Symptoms
Patients experience:
Burning
Numbness
or
Tingling
over the:
Dorsoradial wrist and hand.
Thumb CMC and STT Arthritis
Arthritis involving the:
First carpometacarpal joint
or
Scaphotrapeziotrapezoid joint
can cause radial-sided wrist pain.
Grind Test
A positive:
CMC grind test
supports symptomatic thumb:
CMC arthritis.
Dorsal Wrist Pain
Important causes include:
Extensor tenosynovitis
Ganglion cyst
and other dorsal:
Tendon or ligament disorders.
Extensor Tenosynovitis
Patients typically report:
Dorsal wrist pain
that may radiate:
Proximally
or
Distally.
Cause
The condition is often associated with:
Repetitive activity
and
Overuse.
Examination
Pain may occur with:
Wrist flexion
Wrist extension
and particularly:
Resisted extension.
Synovial Thickening
In some cases, thickened extensor synovium can be palpated during:
Wrist motion.
Ganglion Cyst
A ganglion cyst is the most common mass found on the:
Dorsal wrist.
Origin
Many dorsal ganglia arise near the:
Scapholunate ligament.
Examination
Ganglion cysts are often:
Mobile
and may:
Transilluminate.
Their size may change:
Over time.
Imaging of Ganglion Cyst
Diagnosis is usually clinical.
If uncertain, or if the lesion is in an unusual location,:
Ultrasound
or
MRI
may be useful.
Ulnar-Sided Wrist Pain
Important causes include:
Distal radioulnar joint instability or arthritis
FCU tendinopathy
ECU tendinopathy
Hook of hamate fracture
TFCC tear
Ulnocarpal impaction
and
Lunotriquetral ligament injury.
Distal Radioulnar Joint Instability
Pain is usually localized over the:
Distal radioulnar joint
and is worsened by:
Pronation
and
Supination.
DRUJ Examination
Instability may be assessed by translating the:
Ulna
relative to a stabilized:
Radius.
Piano-Key Sign
Abnormal mobility of the distal ulna may produce a:
Piano-key sign.
DRUJ Imaging
Radiographs may demonstrate abnormal:
Distal radioulnar spacing or alignment.
If radiographs are inconclusive,:
CT
can help evaluate:
DRUJ congruity and instability.
DRUJ Arthritis
Degenerative changes may include:
Joint-space narrowing
Subchondral sclerosis
and
Osteophytes.
Flexor Carpi Ulnaris Tendinopathy
FCU tendinopathy produces pain near the:
Volar-ulnar wrist.
Examination
Pain is typically reproduced by:
Resisted wrist flexion
and
Ulnar deviation.
Extensor Carpi Ulnaris Tendinopathy
ECU tendinopathy causes pain along the:
Dorsal-ulnar wrist.
Examination
Pain may be reproduced by resisted:
Ulnar deviation
particularly with the forearm in:
Supination.
Hook of Hamate Fracture
This injury is particularly important in athletes such as:
Golfers
and
Racquet-sport players.
Mechanism
The injury may result from direct pressure or impact through:
A club
Bat
or
Racquet handle
against the:
Ulnar palm.
Examination
Tenderness is present over the:
Hook of the hamate.
Pain may also be reproduced with resisted flexion of the:
Ring and small fingers.
Imaging
A:
Carpal tunnel view
or CT may be needed because standard radiographs may fail to show the:
Fracture.
TFCC Tear
A triangular fibrocartilage complex tear typically causes:
Ulnar-sided wrist pain
often accompanied by:
Clicking.
TFCC Provocative Test
Pain may be reproduced by:
Axial loading
while rotating an:
Ulnar-deviated wrist.
Ulnocarpal Impaction
Ulnocarpal impaction syndrome causes pain with:
Grip
particularly when the forearm is:
Pronated.
Ulnar Variance
The condition is more common when there is:
Positive ulnar variance.
Lunotriquetral Ligament Injury
Lunotriquetral ligament injury may produce:
Ulnar-sided wrist pain
and
Instability.
LT Shuck Test
The lunate and triquetrum are moved in opposite directions.
Findings such as:
Pain
Crepitus
or excessive:
Translation
support an LT ligament injury.
Volar Wrist Pain
Common causes include:
Flexor tenosynovitis
Carpal tunnel syndrome
and
Volar ganglion cyst.
Flexor Tenosynovitis
Patients usually describe:
Palmar wrist pain
associated with repetitive:
Overuse.
Examination
Pain is worsened by:
Wrist motion
and
Resisted wrist flexion.
Symptoms may radiate:
Proximally
or
Distally.
Carpal Tunnel Syndrome
CTS is the most common:
Compression neuropathy of the upper extremity.
Symptoms
Patients may report:
Wrist discomfort
Numbness
Tingling
Clumsiness
and
Weakness.
Sensory Distribution
Symptoms typically involve the:
Thumb
Index finger
Middle finger
and
Radial half of the ring finger.
Nocturnal Symptoms
Patients frequently awaken at night with:
Numbness or paresthesias.
Provocative Tests
Useful maneuvers include:
Tinel sign
Phalen test
and
Flexion-compression testing.
Late CTS Findings
Advanced median neuropathy may produce:
Reduced sensation
and
Thenar atrophy.
Generalized Wrist Pain
Diffuse pain may result from:
Osteoarthritis
Inflammatory arthritis
or
Infection.
Osteoarthritis
Degenerative arthritis may affect the:
Radiocarpal
Intercarpal
or
CMC joints.
History
Patients may have a history of:
Previous trauma
or longstanding:
Degeneration.
Examination
Typical findings include:
Pain
Stiffness
Swelling
and
Reduced range of motion.
Osteoarthritis Radiographs
Common findings include:
Joint-space narrowing
Subchondral sclerosis
and
Osteophyte formation.
Inflammatory Arthritis
Inflammatory disorders such as:
Rheumatoid arthritis
may cause:
Synovitis
Tendon-sheath swelling
and later:
Joint deformity.
Inflammatory Arthritis Radiographs
Possible findings include:
Joint-space narrowing
Periarticular osteopenia
Bone erosions
and
Deformity.
Wrist Infection
Septic arthritis of the:
Radiocarpal joint
is uncommon but potentially destructive.
Risk Factors
Risk is increased in:
Immunocompromised patients
and individuals with a history of:
Intravenous drug use.
Signs of Infection
Possible findings include:
Severe pain
Swelling
Erythema
Warmth
and
Marked reduction in motion.
Pain With Motion
Severe pain with:
Passive and active wrist motion
is particularly concerning for:
Septic arthritis.
Laboratory Findings
Possible abnormalities include elevated:
White blood cell count
ESR
and
CRP.
Normal serum tests do not completely exclude:
Infection.
Joint Aspiration
When septic arthritis is suspected, the joint should be:
Aspirated urgently.
Synovial fluid should be sent for:
Cell count
Differential
Gram stain
and
Culture.
Synovial WBC
A very high synovial leukocyte count with a predominance of:
Neutrophils
strongly supports infection.
Historical thresholds such as:
>80,000 cells/µL with >75% polymorphonuclear cells
have been described, but no single value alone confirms or excludes:
Septic arthritis.
Laboratory Tests
Laboratory evaluation is most useful when:
Infection
or systemic inflammatory disease is suspected.
Infection Markers
Obtain:
CBC
ESR
and
CRP
when evaluating possible:
Septic arthritis.
Imaging
Plain Radiographs
Initial imaging usually includes:
PA
Lateral
and
Oblique wrist radiographs.
Scaphoid View
A dedicated:
Scaphoid view
is useful when a:
Scaphoid fracture
is suspected.
Carpal Tunnel View
A:
Carpal tunnel view
can improve visualization of the:
Hook of hamate.
MRI
MRI, preferably with high-resolution technique, may be useful for suspected:
TFCC
Scapholunate
or
Lunotriquetral ligament tears.
Limitations of MRI
MRI findings should be interpreted in combination with:
History
and
Physical examination
because incidental abnormalities can occur.
Differential Diagnosis
Radial-Sided Pain
Consider:
de Quervain tenosynovitis
Scaphoid fracture or nonunion
Scapholunate ligament injury
Thumb CMC arthritis
STT arthritis
Radiocarpal arthritis
and
Wartenberg syndrome.
Dorsal Pain
Consider:
Extensor tenosynovitis
Ganglion cyst
and
ECU tendinopathy.
Ulnar-Sided Pain
Consider:
DRUJ instability
FCU tendinopathy
ECU tendinopathy
Hook of hamate fracture
TFCC tear
Ulnocarpal impaction
and
Lunotriquetral ligament injury.
Volar Pain
Consider:
Flexor tenosynovitis
Carpal tunnel syndrome
and
Volar ganglion cyst.
Generalized Pain
Consider:
Osteoarthritis
Inflammatory arthritis
and
Infection.
Treatment
Treatment depends entirely on the:
Underlying diagnosis.
Tendinitis and Tenosynovitis
Initial treatment may include:
Rest
Activity modification
Cold therapy
Immobilization
and
NSAIDs.
Corticosteroid Injection
Selected persistent tendon-sheath disorders may benefit from:
Local corticosteroid injection.
Nondisplaced Fractures
Stable nondisplaced fractures are generally treated with:
Immobilization
and appropriate:
Analgesia.
Rheumatoid Arthritis
Rheumatoid wrist disease requires treatment of the underlying systemic:
Inflammatory disorder.
Management should be coordinated with a:
Rheumatologist.
Ganglion Cyst
Observation is appropriate for many asymptomatic:
Ganglion cysts.
Aspiration
Dorsal ganglia may be:
Aspirated
but recurrence is:
Common.
Excision
Surgical excision generally has a lower recurrence rate than:
Aspiration
but still carries risks of:
Stiffness
scar sensitivity
and
Recurrence.
Carpal Tunnel Syndrome
Mild to moderate CTS can initially be treated with:
Neutral-position wrist splinting
Activity modification
and selected:
Corticosteroid injection.
Role of Injection
Steroid injection may provide substantial:
Temporary symptom relief
and can delay or occasionally avoid:
Surgery.
It does not reliably provide permanent cure in all:
Patients.
Wrist Infection
Suspected septic wrist requires urgent:
Hospital-based treatment.
Aspiration and Cultures
Synovial fluid should be obtained for:
Gram stain
and
Culture
before antibiotics whenever this can be performed without delaying:
Treatment.
Antibiotics
After cultures are obtained,:
Intravenous antibiotics
should be started promptly.
Surgical Drainage
Many septic wrists require:
Arthroscopic or open irrigation and debridement.
Serial Aspiration
Repeated aspiration may be appropriate in selected:
Patients
when adequate drainage can be achieved and close monitoring is:
Available.
Rehabilitation After Infection
Once infection is controlled, early:
Range of motion
is important to minimize:
Joint stiffness.
Medication
First-line medication depends on the diagnosis.
Possible therapies include:
NSAIDs
Local corticosteroid injection
and
Intravenous antibiotics
for septic arthritis.
Surgery
Operative treatment is reserved for specific:
Structural or refractory conditions.
de Quervain Surgery
Persistent de Quervain disease despite adequate nonoperative management may require:
First dorsal compartment release.
Scaphoid Fracture Surgery
Displaced scaphoid fractures commonly require:
Internal fixation.
Selected nondisplaced fractures may be treated with:
Cast immobilization
or
Internal fixation
depending on location, patient factors, and functional demands.
DRUJ Instability
Persistent DRUJ instability may require:
Arthroscopy
TFCC repair
or open:
Reconstruction.
Fracture-Associated DRUJ Instability
If instability accompanies fractures of the:
Distal radius
or
Ulna
fracture fixation may be required.
Temporary:
DRUJ pinning
may be used in selected unstable injuries.
Hook of Hamate Fracture
Hook fractures have a relatively high risk of:
Nonunion.
Small Hook Fragment
A persistently symptomatic small fragment may be treated with:
Surgical excision.
Base Fracture
A fracture through the base of the hook may be treated with:
Open reduction and internal fixation
when appropriate.
Flexor Tenosynovitis
Chronic refractory flexor tendon adhesions or mechanical restriction may occasionally require:
Tenolysis
although treatment depends on the specific:
Pathology.
Carpal Tunnel Release
Surgical decompression is considered when:
Nonoperative treatment fails
or when advanced median nerve dysfunction is present.
Advanced CTS Findings
Indications include:
Persistent sensory loss
Thenar weakness or atrophy
and significant abnormalities on:
Nerve conduction studies or EMG.
Arthritis Surgery
Severe wrist arthritis that does not respond to conservative care may require:
Arthroplasty
Resection procedures
or
Partial or total wrist fusion.
Follow-Up
Follow-up is determined by:
Diagnosis
Treatment
and progression of:
Symptoms.
Prognosis
Most causes of wrist pain can be substantially improved when the underlying disorder is:
Correctly identified
and treated appropriately.
Clinical Summary
First step: Localize the pain as radial, dorsal, ulnar, volar, or diffuse.
Radial pain: Think de Quervain disease, scaphoid fracture, scapholunate injury, CMC/STT arthritis, and Wartenberg syndrome.
Dorsal pain: Common causes include extensor tenosynovitis and ganglion cyst.
Ulnar pain: Consider TFCC tear, DRUJ pathology, ECU/FCU tendinopathy, hook of hamate fracture, ulnocarpal impaction, and lunotriquetral injury.
Volar pain: Common causes are flexor tenosynovitis and carpal tunnel syndrome.
Diffuse pain: Consider osteoarthritis, inflammatory arthritis, and infection.
Imaging: Begin with PA, lateral, and oblique wrist radiographs; add scaphoid, carpal tunnel, CT, or MRI views as dictated by the suspected diagnosis.
Red flag: Severe pain with passive motion, swelling, warmth, erythema, or systemic illness should raise concern for septic arthritis and prompt urgent aspiration and treatment.
Treatment: Most diagnoses begin with activity modification, immobilization, analgesia, and diagnosis-specific therapy, while surgery is reserved for unstable, displaced, compressive, infectious, or refractory pathology.
Key Principle
Wrist pain is a symptom rather than a diagnosis, and the most useful first step is careful:
Anatomic localization.
Radial, dorsal, ulnar, volar, and generalized pain patterns each have characteristic:
Differential diagnoses and provocative findings.
A thorough examination should assess:
Tenderness, motion, tendon function, ligament stability, nerve symptoms, and joint inflammation.
Plain radiographs are the initial imaging study for most patients, while:
CT
MRI
or
Arthroscopy
may be required for selected fractures, ligament injuries, or unclear diagnoses.
Urgent recognition of:
Infection, unstable fracture, neurovascular compromise, or advanced nerve compression
is essential to prevent long-term:
Loss of wrist and hand function.