Pathology - Anemia of Chronic Inflammation
Due to long-term systemic conditions such as rheumatoid arthritis and persistent infection (such as HIV). or malignancy Study of the nature and causes of diseases. Peripheral blood smear: Exhibiting normal chromaticity. Normal-sized red blood cells Pathophysiology refers to the study of the abnormal physiological processes that occur in the body as a result of disease or injury. Elevated levels of cytokines and hepcidin during an inflammatory state hinder the efficient use of iron by the bone marrow, resulting in reduced production of red blood cells. Medical Presentation Anemia is characterized by the presence of fatigue and pallor. Laboratory results indicate a little decrease in heterozygosity, low levels of iron in the blood serum, normal to low levels of total iron-binding capacity (TIBC), and normal to increased levels of serum ferritin, suggesting an increase in iron storage in the macrophages of the bone marrow. Therapy Address the underlying condition: administer synthetic erythropoietin or perform blood transfusions if the condition is severe.
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