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Pathology -Benign vulval tumours
Bartholin duct cysts
• Arise due to obstruction of a Bartholin’s gland duct.
• Present as painless lumps of the vulva in young women.
• Histologically, they are lined by transitional-type epithelium with areas
of squamous metaplasia.
Papillary hidradenoma
• Benign sweat gland tumour which usually presents in middle-aged
women as a small painless vulval lump.
• Histologically, they are well-circumscribed papillary tumours of the
dermis. The epithelium covering the papillae is double-layered, with
inner tall columnar cells and outer small myoepithelial cells.
Condylomas
• Solitary or multiple lesions related to certain types of human papilloma
virus (HPV) infection.
• Histologically, they show papillary squamous proliferations with
koilocytes (keratinocytes showing HPV cytopathic effect).
• Widespread vulval condylomas may be seen in the immunosuppressed
.
Granular cell tumour
• Uncommon neural tumour that may occur in the vulva.
• Histologically composed of nests of large polygonal cells with abundant
granular cytoplasm.
• The vast majority behave in a benign fashion.
Angiomyofi broblastoma
• Benign mesenchymal neoplasm that occurs almost exclusively in the
vulvovaginal region of young women.
• Presents as a small subcutaneous lump, often mistaken for a cyst.
• Histologically, they are well-circumscribed lesions composed of dilated
capillary-sized vessels set in an oedematous stroma containing many
plump epithelioid stromal cells.
Cellular angiofi broma
• Benign mesenchymal neoplasm presenting as a small painless
subcutaneous mass in the vulvovaginal region of reproductive age
women.
• Histologically, they are well-circumscribed cellular lesions composed of
bland spindle cells and many small thick-walled blood vessels.
Deep angiomyxoma
• Locally infi ltrative, but non-metastasizing, mesenchymal neoplasm that
presents as a large deep-seated mass in the pelvis and perineum of
reproductive age women.
• Histologically, they are infi ltrative, paucicellular tumours composed of
small numbers of bland spindle cells set in a myxoid stroma containing
thick-walled blood vessels
Bartholin duct cysts
• Arise due to obstruction of a Bartholin’s gland duct.
• Present as painless lumps of the vulva in young women.
• Histologically, they are lined by transitional-type epithelium with areas
of squamous metaplasia.
Papillary hidradenoma
• Benign sweat gland tumour which usually presents in middle-aged
women as a small painless vulval lump.
• Histologically, they are well-circumscribed papillary tumours of the
dermis. The epithelium covering the papillae is double-layered, with
inner tall columnar cells and outer small myoepithelial cells.
Condylomas
• Solitary or multiple lesions related to certain types of human papilloma
virus (HPV) infection.
• Histologically, they show papillary squamous proliferations with
koilocytes (keratinocytes showing HPV cytopathic effect).
• Widespread vulval condylomas may be seen in the immunosuppressed
.
Granular cell tumour
• Uncommon neural tumour that may occur in the vulva.
• Histologically composed of nests of large polygonal cells with abundant
granular cytoplasm.
• The vast majority behave in a benign fashion.
Angiomyofi broblastoma
• Benign mesenchymal neoplasm that occurs almost exclusively in the
vulvovaginal region of young women.
• Presents as a small subcutaneous lump, often mistaken for a cyst.
• Histologically, they are well-circumscribed lesions composed of dilated
capillary-sized vessels set in an oedematous stroma containing many
plump epithelioid stromal cells.
Cellular angiofi broma
• Benign mesenchymal neoplasm presenting as a small painless
subcutaneous mass in the vulvovaginal region of reproductive age
women.
• Histologically, they are well-circumscribed cellular lesions composed of
bland spindle cells and many small thick-walled blood vessels.
Deep angiomyxoma
• Locally infi ltrative, but non-metastasizing, mesenchymal neoplasm that
presents as a large deep-seated mass in the pelvis and perineum of
reproductive age women.
• Histologically, they are infi ltrative, paucicellular tumours composed of
small numbers of bland spindle cells set in a myxoid stroma containing
thick-walled blood vessels
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