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Pathology - Esophageal polyps and nodules
Squamous papilloma • An atypical lesion typically observed as a little white polyp in the distal esophagus during endoscopy. • While the association with human papillomavirus (HPV) infection has been hypothesized, the majority of investigations have failed to detect HPV material within these lesions.
Histological examination reveals non-descript squamous epithelium exhibiting papillary projections.
leiomyoma • Rare benign smooth muscle neoplasm originating from the muscular layers of the esophagus. • Typically manifests as a polypoid mass enveloped by mucosa, which may exhibit surface ulcers.
Histological examination reveals interwoven fascicles of benign smooth muscle cells.
Granular cell tumor • An infrequent neurological neoplasm that may arise throughout the gastrointestinal tract, predominantly in the tongue and esophagus. • A tiny firm mucosal nodule is present in the lower esophagus. •
Histological examination reveals clusters of large polygonal cells with prominent granular cytoplasm. • The majority are benign, while rare instances of malignancy have been documented.
Fibrovascular polyp • Uncommon oesophageal lesion that commonly manifests as dysphagia. • May attain a remarkably large size (up to 25 cm in length), perhaps resulting in regurgitation into the throat or oral cavity. • Endoscopically identifiable as a pedunculated lesion on an elongated stalk. • Histological examination reveals a polypoid lesion enveloped by squamous epithelium, with an underlying stromal core consisting of loose fibrous tissue, adipose tissue, and a conspicuous vascular network.
Squamous papilloma • An atypical lesion typically observed as a little white polyp in the distal esophagus during endoscopy. • While the association with human papillomavirus (HPV) infection has been hypothesized, the majority of investigations have failed to detect HPV material within these lesions.
Histological examination reveals non-descript squamous epithelium exhibiting papillary projections.
leiomyoma • Rare benign smooth muscle neoplasm originating from the muscular layers of the esophagus. • Typically manifests as a polypoid mass enveloped by mucosa, which may exhibit surface ulcers.
Histological examination reveals interwoven fascicles of benign smooth muscle cells.
Granular cell tumor • An infrequent neurological neoplasm that may arise throughout the gastrointestinal tract, predominantly in the tongue and esophagus. • A tiny firm mucosal nodule is present in the lower esophagus. •
Histological examination reveals clusters of large polygonal cells with prominent granular cytoplasm. • The majority are benign, while rare instances of malignancy have been documented.
Fibrovascular polyp • Uncommon oesophageal lesion that commonly manifests as dysphagia. • May attain a remarkably large size (up to 25 cm in length), perhaps resulting in regurgitation into the throat or oral cavity. • Endoscopically identifiable as a pedunculated lesion on an elongated stalk. • Histological examination reveals a polypoid lesion enveloped by squamous epithelium, with an underlying stromal core consisting of loose fibrous tissue, adipose tissue, and a conspicuous vascular network.
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