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Pathology - Gastric polyps
Hyperplastic polyp • A prevalent polyp primarily found in the antrum or body. • A non-neoplastic reactive lesion believed to signify an amplified regenerative reaction to mucosal damage. • Typically linked to underlying stomach conditions, including Helicobacter infection or autoimmune gastritis. • Histological examination reveals a polyp characterized by dilated, elongated, convoluted foveolar epithelium inside an edematous, inflamed lamina propria.
Fundic gland polyp • A prevalent polyp that is found exclusively in the body or fundus. • May manifest spontaneously or in conjunction with familial adenomatous polyposis (FAP). FAP-associated polyps tend to be numerous and manifest at an earlier age. Sporadic polyps are typically not linked to any underlying mucosal condition. • Certain articles have indicated a correlation with proton pump inhibitors; however, this assertion has been contested thereafter. Histological examination reveals a polyp characterized by cystically dilated fundic glands, which are bordered by flattened parietal and chief cells.
Gastric adenoma • Rare neoplastic polyp that may arise in various regions of the stomach. • Microscopically characterized by dysplastic glands featuring stratified hyperchromatic nuclei. • Two variants are identified: intestinal and foveolar kinds. Intestinal forms are significantly more prone to exhibit high-grade dysplasia or contain gastric cancer compared to the foveolar type.
Gastric xanthoma: An uncommon polyp that can manifest in any region of the stomach. • Exhibits a pale yellow nodular owing to its lipid composition. • Histological examination reveals an abundance of lipid-laden macrophages within the lamina propria.
Inflammatory fibroid polyp • Uncommon lesion primarily located in the antrum. • Histological examination reveals a submucosal lesion consisting of innocuous spindle cells organized around prominent arteries, embedded in a loose myxoid stroma including notable eosinophils.
Hyperplastic polyp • A prevalent polyp primarily found in the antrum or body. • A non-neoplastic reactive lesion believed to signify an amplified regenerative reaction to mucosal damage. • Typically linked to underlying stomach conditions, including Helicobacter infection or autoimmune gastritis. • Histological examination reveals a polyp characterized by dilated, elongated, convoluted foveolar epithelium inside an edematous, inflamed lamina propria.
Fundic gland polyp • A prevalent polyp that is found exclusively in the body or fundus. • May manifest spontaneously or in conjunction with familial adenomatous polyposis (FAP). FAP-associated polyps tend to be numerous and manifest at an earlier age. Sporadic polyps are typically not linked to any underlying mucosal condition. • Certain articles have indicated a correlation with proton pump inhibitors; however, this assertion has been contested thereafter. Histological examination reveals a polyp characterized by cystically dilated fundic glands, which are bordered by flattened parietal and chief cells.
Gastric adenoma • Rare neoplastic polyp that may arise in various regions of the stomach. • Microscopically characterized by dysplastic glands featuring stratified hyperchromatic nuclei. • Two variants are identified: intestinal and foveolar kinds. Intestinal forms are significantly more prone to exhibit high-grade dysplasia or contain gastric cancer compared to the foveolar type.
Gastric xanthoma: An uncommon polyp that can manifest in any region of the stomach. • Exhibits a pale yellow nodular owing to its lipid composition. • Histological examination reveals an abundance of lipid-laden macrophages within the lamina propria.
Inflammatory fibroid polyp • Uncommon lesion primarily located in the antrum. • Histological examination reveals a submucosal lesion consisting of innocuous spindle cells organized around prominent arteries, embedded in a loose myxoid stroma including notable eosinophils.
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