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Pathology - Hypoparathyroidism
The condition can be caused by surgical removal of the parathyroid glands, congenital lack of the parathyroid glands (as seen in DiGeorge syndrome), radioactive iodine therapy, or idiopathic autoimmune atrophy of the parathyroids.
Pathology
Gross finding: Slight reduction in the size of the gland.
Microscopic: Fibrotic tissue replaces main cells.
Hypocalcemia symptoms include tetany, prolonged QT interval on ECG, Trousseau sign, and Chvostek sign.
Laboratory results indicate low levels of calcium, reduced parathyroid hormone (PTH) levels, and elevated serum phosphate levels.
Therapy includes calcium and vitamin D supplements.
The condition can be caused by surgical removal of the parathyroid glands, congenital lack of the parathyroid glands (as seen in DiGeorge syndrome), radioactive iodine therapy, or idiopathic autoimmune atrophy of the parathyroids.
Pathology
Gross finding: Slight reduction in the size of the gland.
Microscopic: Fibrotic tissue replaces main cells.
Hypocalcemia symptoms include tetany, prolonged QT interval on ECG, Trousseau sign, and Chvostek sign.
Laboratory results indicate low levels of calcium, reduced parathyroid hormone (PTH) levels, and elevated serum phosphate levels.
Therapy includes calcium and vitamin D supplements.
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