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Pathology - Oligodendroglioma
Uncommon noncancerous growth originating from oligodendrocytes.
Typically impacts individuals in their middle years.
The pathology is a well-defined, slow-growing gray mass typically containing cysts. It commonly occurs in the white matter of the cerebral hemispheres, particularly in the frontal lobe.
Microscopic: Uniform cell sheets with spherical nuclei and clear cytoplasm resembling a fried egg; often contains calcifications and enhanced vascularity.
Clinical Symptoms
Seizures, headaches, papilledema, and other indicators of elevated intracranial pressure.
Imaging reveals the presence of tumor calcification on a CT scan.
Therapy
Surgical removal, subsequent radiation, and chemotherapy.
The average survival time post-diagnosis ranges from 5 to 10 years.
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