Pathology - Ovarian Surface Epithelium Origin Tumors
Risk factors consist of a family history of breast or ovarian cancer, mutations in BRCA1 or BRCA2, and nulliparity. Typically manifests in females over 20 years old. Serous cystadenoma: Benign cysts with fallopian tube-like epithelium present bilaterally. Papillary serous cystadenocarcinoma is characterized by malignant cysts bordered with stratified atypical epithelium, papillary growth, and psammoma structures. Mucinous cystadenoma is characterized by the presence of several benign cysts with columnar cells packed with mucin. Mucinous cystadenocarcinoma is a malignant tumor characterized by mucus-secreting atypical columnar epithelium, loss of gland architecture, and necrosis. Brenner tumor is a benign tumor characterized by clusters of cells that resemble bladder transitional epithelium, found inside a fibrous stroma. Endometrioid tumor: Cancerous tumor that resembles the endometrium. Clear cell tumor: Rare, malignant tumor composed of sheets of clear cells. Clinical Symptoms Subtle abdominal discomfort; severe cases may show weakness, weight loss, and loss of appetite; pseudomyxoma peritonei (buildup of mucinous material in the abdominal cavity) is linked to mucinous cystadenocarcinoma. Laboratory results: Increased levels of CA-125 in ovarian cancer. Treatment involves tumor excision through procedures such as oophorectomy or hysterectomy, followed by chemotherapy. 75% of ovarian cancers are ovarian epithelial tumors.
0 Comments
Leave a Reply. |
Kembara XtraFacts about medicine and its subtopic such as anatomy, physiology, biochemistry, pharmacology, medicine, pediatrics, psychiatry, obstetrics and gynecology and surgery. Categories
All
|