- Published on
Pathology - Pathologies of the larynx
Vocal chord nodules are benign neoplasms of the laryngeal mucosa. Nodules mainly occur in young women and are linked to vocal abuse. • Exhibit alterations in vocalization. • Minor lesions located in the central third of both vocal cords. Histology reveals a lump with an edematous stroma that subsequently turns fibrotic.
Vocal fold polyp is a non malignant proliferation of the laryngeal mucosa. • Manifestations can arise at any age and are equally prevalent among genders. • Exhibits alterations in vocal quality. • Pertains to the ventricular space or Reinke's space of a single vocal chord. Histology reveals a polyp characterized by a stroma that may exhibit variable oedema, myxoid, hyaline, or fibrous properties.
Laryngeal amyloidosis is a localized variant of amyloidosis. • Typically occurs in the false vocal cords. • Manifestations include alterations in vocal quality. Histological analysis reveals the accumulation of amorphous eosinophilic substance behind the epithelium. Amyloid exhibits staining with Congo Red and reveals chromatic alterations under polarized light. The amyloid typically originates from light chain immunoglobulins.
Squamous papillomas is a predominant benign laryngeal neoplasms. • Linked to human papillomavirus (HPV) types 6 and 11. Bimodal age of incidence: under 5 years and between 20 to 40 years. • Exhibit alterations in vocalization. Histology reveals branching exophytic papillary fronds enveloped by non-descript squamous epithelium. • Pediatric patients typically exhibit a more aggressive disease with early recurrences and an increased likelihood of metastasis outside the larynx. • Adult patients generally demonstrate a more favorable prognosis with less frequent recurrences.
Squamous cell carcinoma is a predominant malignant tumor of the larynx. • Predominantly affects older persons, with a preference for males. • Correlation with tobacco and alcohol misuse. • Exhibits alterations in vocal quality. Histological examination reveals infiltrating nests of malignant epithelial cells with squamous differentiation. • Prognosis is contingent upon the stage of the tumor at presentation.
Vocal chord nodules are benign neoplasms of the laryngeal mucosa. Nodules mainly occur in young women and are linked to vocal abuse. • Exhibit alterations in vocalization. • Minor lesions located in the central third of both vocal cords. Histology reveals a lump with an edematous stroma that subsequently turns fibrotic.
Vocal fold polyp is a non malignant proliferation of the laryngeal mucosa. • Manifestations can arise at any age and are equally prevalent among genders. • Exhibits alterations in vocal quality. • Pertains to the ventricular space or Reinke's space of a single vocal chord. Histology reveals a polyp characterized by a stroma that may exhibit variable oedema, myxoid, hyaline, or fibrous properties.
Laryngeal amyloidosis is a localized variant of amyloidosis. • Typically occurs in the false vocal cords. • Manifestations include alterations in vocal quality. Histological analysis reveals the accumulation of amorphous eosinophilic substance behind the epithelium. Amyloid exhibits staining with Congo Red and reveals chromatic alterations under polarized light. The amyloid typically originates from light chain immunoglobulins.
Squamous papillomas is a predominant benign laryngeal neoplasms. • Linked to human papillomavirus (HPV) types 6 and 11. Bimodal age of incidence: under 5 years and between 20 to 40 years. • Exhibit alterations in vocalization. Histology reveals branching exophytic papillary fronds enveloped by non-descript squamous epithelium. • Pediatric patients typically exhibit a more aggressive disease with early recurrences and an increased likelihood of metastasis outside the larynx. • Adult patients generally demonstrate a more favorable prognosis with less frequent recurrences.
Squamous cell carcinoma is a predominant malignant tumor of the larynx. • Predominantly affects older persons, with a preference for males. • Correlation with tobacco and alcohol misuse. • Exhibits alterations in vocal quality. Histological examination reveals infiltrating nests of malignant epithelial cells with squamous differentiation. • Prognosis is contingent upon the stage of the tumor at presentation.
0 Comments
