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Pathology - Right ventricular failure
Definition: A syndrome caused by inadequate right ventricular output.
Epidemiology • Rare. • Observed far less often than LVF. Aetiology Most instances are attributable to chronic pulmonary conditions, including chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, bronchiectasis, and recurrent pulmonary emboli. Less common etiologies including ischemic heart disease impacting the right ventricle and right-sided valvular heart disease.
Pathogenesis • In the majority of instances, right ventricular failure (RVF) arises from pulmonary hypertension induced by chronic pulmonary conditions. • Pulmonary hypertension elevates the workload of the right ventricle by necessitating increased chamber pressure to sustain sufficient output. • Initially, right ventricular hypertrophy occurs, but ultimately, the chamber undergoes dilation and failure
.Presentation: • Deterioration of pre-existing dyspnea and onset of peripheral edema.
Macroscopy • The right ventricle exhibits hypertrophy and dilation. Histopathology • Histology is non-specific, typically exhibiting patchy myocyte hypertrophy or atrophy accompanied by interstitial fibrosis.
Prognosis • Elevated risk of mortality due to concurrent cardiac and respiratory failure. • Numerous patients experience abrupt death from a lethal ventricular arrhythmia originating in the compromised right ventricle.
Definition: A syndrome caused by inadequate right ventricular output.
Epidemiology • Rare. • Observed far less often than LVF. Aetiology Most instances are attributable to chronic pulmonary conditions, including chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, bronchiectasis, and recurrent pulmonary emboli. Less common etiologies including ischemic heart disease impacting the right ventricle and right-sided valvular heart disease.
Pathogenesis • In the majority of instances, right ventricular failure (RVF) arises from pulmonary hypertension induced by chronic pulmonary conditions. • Pulmonary hypertension elevates the workload of the right ventricle by necessitating increased chamber pressure to sustain sufficient output. • Initially, right ventricular hypertrophy occurs, but ultimately, the chamber undergoes dilation and failure
.Presentation: • Deterioration of pre-existing dyspnea and onset of peripheral edema.
Macroscopy • The right ventricle exhibits hypertrophy and dilation. Histopathology • Histology is non-specific, typically exhibiting patchy myocyte hypertrophy or atrophy accompanied by interstitial fibrosis.
Prognosis • Elevated risk of mortality due to concurrent cardiac and respiratory failure. • Numerous patients experience abrupt death from a lethal ventricular arrhythmia originating in the compromised right ventricle.
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