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Pathology - Scrotal disorders
Epidermoid cysts are a common source of scrotal cutaneous lumps, characterized by yellow keratinous debris and squamous epithelium with epidermoid-type keratinization.

Scrotal calcinosis is a rare condition that causes numerous calcified nodules on the scrotal skin. The dystrophic calcification is likely caused by ancient epidermoid cysts.

Angiokeratomas are benign vascular lesions that appear as several tiny blue/red lesions on the scrotal skin. Histologically, they are made up of dilated vascular channels in the papillary dermis, accompanied by hyperplasia and hyperkeratosis of the epidermis.
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Fournier’s gangrene • Diabetes and immunosuppression are the main risk factors for this clinical variant of necrotizing fasciitis which affects the penis, scrotum, perineum, and abdominal wall of men. • It is a polymicrobial infection caused by a mix of aerobic and anaerobic bacteria. • Histology reveals a severe necrotizing inflammatory process involving the skin and deep subcutaneous tissue. • Mortality rates range from 15-20%.
Scrotal squamous cell cancer. • A uncommon cancer that has historically been linked to occupational exposure to toxins among chimney workers.


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