Pathology - Takayasu Arteritis
The cause is yet unidentified, although it is believed that immunological systems may be involved. Primarily impacts females in their thirties to fifties. Study of the nature and causes of diseases. Gross Pathology: This condition involves the disease of medium and big arteries, which leads to the thickening of the aortic arch or the proximal great vessels, culminating in vascular insufficiency. Study of cellular and tissue abnormalities at a microscopic level. The tissue sample shows the presence of a single kind of immune cells surrounding and cutting the small blood vessels in the outer layer and middle layer of the blood vessel wall, as well as the formation of small nodules with large immune cells. Symptoms and signs The patient presents with fever, weak pulses in the upper extremities (known as "pulseless disease"), joint pain, fainting, skin nodules, excessive sweating at night, difficulty walking due to pain (bruits may be detected over the subclavian arteries), and visual and neurological problems. Laboratory findings: Significant increase in erythrocyte sedimentation rate (ESR) Treatment options for this condition include the administration of corticosteroids. In more severe cases, additional medications such as cyclophosphamide or methotrexate may be necessary.
0 Comments
Leave a Reply. |
Kembara XtraFacts about medicine and its subtopic such as anatomy, physiology, biochemistry, pharmacology, medicine, pediatrics, psychiatry, obstetrics and gynecology and surgery. Categories
All
|