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Pathology – Varicose Veins
Definition: Tortuous and dilated superficial leg veins resulting from valvular incompetence.
Epidemiology
• Impact as much as 20% of the population. • Significant female predominance (5:4 ratio 9:1). Aetiology • The majority of cases are primary and idiopathic. • Secondary causes including pregnancy, substantial fibroids, and ovarian masses.
Mechanism of Disease Development
• Believed that valve cusps undergo degeneration and form perforations. • Valve incompetence elevates stress on the downstream valve. • Ultimately, a column of valves becomes inadequate, resulting in venous dilation.
Presentation
• The majority of patients present because of the unattractive appearance of the veins. • Discomfort, hurting, itching, and swelling may be present. • Symptoms may intensify towards the day's conclusion.
Complications
• Stasis dermatitis (varicose). • Varicose ulceration. • Lipodermatosclerosis. • Hemorrhaging. • Thrombosis (superficial thrombophlebitis)



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