Pharmacology - Allopurinol

Pharmacology - Allopurinol 
Reduces the amount of uric acid that is present in the body.

Inhibits xanthine oxidase as well as the biotransformation of purines into xanthine are the modes of action of this drug.

Alloxanthine, which has a half life of approximately 18–30 hours and is the component that inhibits xanthine oxidase, is converted to alloxanthine when it is administered orally and is easily absorbed.

Use in Clinical Settings 
in order to avoid experiencing bouts of gout.

Adverse Effects 
Disorders of the gastrointestinal tract! Rash and blood dyscrasias are both possible outcomes.

NSAIDs are the medications that are used to treat acute attacks of gout; allopurinol is not used to treat these attacks.
As a result of its ability to disrupt the metabolic processes of oral anticoagulants, allopurinol has the potential to enhance the effects of azathioprine and cyclophosphamide.

It is a Drug That 
Probenicid is comparable to uricosuric due to the fact that it likewise functions by raising the amount of uric acid that is excreted through an effect on the proximal tubule in the nephron; however, it is solely utilized for the purpose of preventing gout attacks.