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Pharmacology - Caspofungin
Action Fungicidal via weakening the fungus cell wall.
Method of Operation
prevents the synthesis of 1,3-beta-D-glucan, which is absent from mammalian cells yet is an essential part of the fungal cell wall.
Given i.v. Half-life ~9h.
Application in Clinical Practice
Candidiasis; aspergillosis.
Adverse Reactions
GIT disturbances; headache, dizziness, rash.
Action Fungicidal via weakening the fungus cell wall.
Method of Operation
prevents the synthesis of 1,3-beta-D-glucan, which is absent from mammalian cells yet is an essential part of the fungal cell wall.
Given i.v. Half-life ~9h.
Application in Clinical Practice
Candidiasis; aspergillosis.
Adverse Reactions
GIT disturbances; headache, dizziness, rash.
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