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Pharmacology - Cytarabine
Action of Cytarabine
Pyrimidine analogue that is metabolized in the cell to the trisphosphate which inhibits DNA polymerase.given intrathecally, subcutaneously, or IV.Thorough haematological observation is required.
Application in Clinical Practice
Leukemia myeloblastic acute.
Side Effects
myelosuppression. GIT dysfunction; ataxia of the cerebellum.
Action of Cytarabine
Pyrimidine analogue that is metabolized in the cell to the trisphosphate which inhibits DNA polymerase.given intrathecally, subcutaneously, or IV.Thorough haematological observation is required.
Application in Clinical Practice
Leukemia myeloblastic acute.
Side Effects
myelosuppression. GIT dysfunction; ataxia of the cerebellum.
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