​Pharmacology - Donepezil

​Pharmacology - Donepezil 
Alzheimer's disease symptoms are alleviated by the administered dose of donepezil.

Method of Operation 
The inhibition of acetylcholinesterase can be reversed on its own. Increases the amount of cholinergic transmission that occurs in the hippocampus and the cerebral cortex. To be taken orally. There is a long half life of 70 hours for donepezil. 7 hours is the half life of galantamine. One and a half hours is the half-life of rivastigmine.

Use in Clinical Settings 
Alzheimer's disease that is mild to moderate in severity, which offers some relief from the symptoms but does not have any impact on the progression of the disease.

Effects That Are Bad
Side effects that are predictable related to parasympathomimetic include nausea, diarrhea, vomiting, bradycardia, and an increase in the amount of gastric acid secretion. In addition, anorexia can be accompanied by weight loss and insomnia.