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MEDICINE 

​Pharmacology - Finasteride

12/29/2023

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​Pharmacology - Finasteride 
Interaction of Finasteride 
Finasteride is able to inhibit the 5 alpha-reductase enzyme, which is responsible for the conversion of testosterone to dihydrotestosterone. Dihydrotestosterone has a higher affinity for the androgen receptor than the parent molecule.
As an androgen-receptor antagonist, flutamide is a hormonal agent.

When taken orally, the half-life is approximately seven hours.

Use in Clinical Settings
Prostatic hyperplasia that is not harmful (however it is important to remember that alpha-adrenoceptor blockers are more effective). In the treatment of prostate cancer, flutamide is utilized.

Negative consequences 
Low libido and erectile dysfunction as symptoms.
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