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Pharmacology - Finasteride
Interaction of Finasteride
Finasteride is able to inhibit the 5 alpha-reductase enzyme, which is responsible for the conversion of testosterone to dihydrotestosterone. Dihydrotestosterone has a higher affinity for the androgen receptor than the parent molecule.
As an androgen-receptor antagonist, flutamide is a hormonal agent.
When taken orally, the half-life is approximately seven hours.
Use in Clinical Settings
Prostatic hyperplasia that is not harmful (however it is important to remember that alpha-adrenoceptor blockers are more effective). In the treatment of prostate cancer, flutamide is utilized.
Negative consequences
Low libido and erectile dysfunction as symptoms.
Interaction of Finasteride
Finasteride is able to inhibit the 5 alpha-reductase enzyme, which is responsible for the conversion of testosterone to dihydrotestosterone. Dihydrotestosterone has a higher affinity for the androgen receptor than the parent molecule.
As an androgen-receptor antagonist, flutamide is a hormonal agent.
When taken orally, the half-life is approximately seven hours.
Use in Clinical Settings
Prostatic hyperplasia that is not harmful (however it is important to remember that alpha-adrenoceptor blockers are more effective). In the treatment of prostate cancer, flutamide is utilized.
Negative consequences
Low libido and erectile dysfunction as symptoms.
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