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Pharmacology - Ivermectin
Ivermectin Action
Acts at the worm’s neuromuscular junction, inducing paralysis either by increasing GABA-mediated inhibition or by activating an invertebrate-specific glutamate-gated chloride channel.
Given orally.
Clinical Case
Onchocerciasis (drug of choice); strongyloidiasis.
Precautions to Take
Infrequent: itching, rash, GIT problems, dizziness, tiredness.
Ivermectin Action
Acts at the worm’s neuromuscular junction, inducing paralysis either by increasing GABA-mediated inhibition or by activating an invertebrate-specific glutamate-gated chloride channel.
Given orally.
Clinical Case
Onchocerciasis (drug of choice); strongyloidiasis.
Precautions to Take
Infrequent: itching, rash, GIT problems, dizziness, tiredness.
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