Pharmacology - Nevirapine

Pharmacology - Nevirapine 
How Nevirapine Works: It stops the AIDS virus's HIV reverse transcriptase from working.
It works on HIV-1 but not on HIV-2.

How it works 
It binds to the virus reverse transcriptase enzyme and breaks it down.
Given by mouth; the level in the cerebrospinal fluid is 45% of the level in the plasma.

Use in Medicine
 HIV-1 infection while taking other antiretrovirals. Can cut the risk of passing the virus from mother to baby by about 50%.

Bad Side Effects 
Harm to the liver. Itchy skin, Stevens-Johnson syndrome. GIT problems and myalgia are less common.
Effavirenz can make it hard to sleep and think.

How Nevirapine Works: It stops the AIDS virus's HIV reverse transcriptase from working.
It works on HIV-1 but not on HIV-2.

How it works 
It binds to the virus reverse transcriptase enzyme and breaks it down.
Given by mouth; the level in the cerebrospinal fluid is 45% of the level in the plasma.

Use in Medicine
 HIV-1 infection while taking other antiretrovirals. Can cut the risk of passing the virus from mother to baby by about 50%.

Bad Side Effects 
Harm to the liver. Itchy skin, Stevens-Johnson syndrome. GIT problems and myalgia are less common.
Effavirenz can make it hard to sleep and think.