​Pharmacology - Paclitaxel

​Pharmacology - Paclitaxel 
Paclitaxel 
Connects to tubulin and maintains microtubule polymerization, or "freezing," to inhibit the development of spindles during mitosis and cell division. Given by i.v. infusion.

Medical Application
Cancers of ovary and breast, non-small-cell lung cancer.

Potential Side Effects
Hair thinning, bradycardia, myelosuppression, peripheral neuropathy, hypersensitivity responses, muscular and joint discomfort. Mild gastrointestinal distress.