​Pharmacology - Praziquantel

​Pharmacology - Praziquantel 
Praziquantel Action 
It produces an increase in the calcium permeability of the cell membranes, facilitating calcium in€ux, resulting in prolonged contraction of muscle with eventual paralysis and death

Mode of Action 
Given orally, well absorbrd, metabolised to inactive products. Plasma half-life 60–90min.

Use in Clinical Settings 
Schistosomiasis, cysticercosis.

Precautions to Take
 Few and minor: sometimes GIT disruptions.