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Pharmacology - Testosterone
The Action of Testosterone
The effects of this substance are identical to those of endogenous testosterone; however, the effects will vary depending on the age patient.
Method of Operation
The hormone is converted into dihydrotestosterone, which enters cells and interacts with nuclear receptors to initiate transcription of some genes (which ultimately leads to DNA-directed RNA and protein synthesis) while simultaneously suppressing the expression of other genes.
It is possible to administer the medication orally, buccally, intramuscularly, or transdermally.
Hypogonadism is treated with replacement treatment in clinical settings.
Adverse Effects
A gradual decline in gonadotrophin secretion, which ultimately leads to infertility; oedema as a result of the retention of salt and excessive water.
The Action of Testosterone
The effects of this substance are identical to those of endogenous testosterone; however, the effects will vary depending on the age patient.
Method of Operation
The hormone is converted into dihydrotestosterone, which enters cells and interacts with nuclear receptors to initiate transcription of some genes (which ultimately leads to DNA-directed RNA and protein synthesis) while simultaneously suppressing the expression of other genes.
It is possible to administer the medication orally, buccally, intramuscularly, or transdermally.
Hypogonadism is treated with replacement treatment in clinical settings.
Adverse Effects
A gradual decline in gonadotrophin secretion, which ultimately leads to infertility; oedema as a result of the retention of salt and excessive water.
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