Symptoms and Signs - Differential Diagnosis of Ataxia

1/26/2024

Symptoms and Signs - Differential Diagnosis of Ataxia
• Wilson’s disease (hepatolenticular degeneration)
• Vitamin B12 deficiency
• Vertebral-basilar artery ischemia
• Toxins: phenytoin, alcohol, sedatives, organophosphates
• Tabes dorsalis
• Paraneoplastic syndromes
• Parainfectious: Guillain-Barré syndrome, acute ataxia of childhood and young adults
• Nutritional (Wernicke’s encephalopathy)
• Myopathy
• Multiple sclerosis and other demyelinating diseases
• Meningomyelopathy
• Labyrinthine destruction: neoplasm, injury, inflammation, compression
• Hysteria
• Hypothyroidism
• Frontal lobe lesions: tumors, thrombosis of anterior cerebral artery, hydrocephalus
• Diabetic neuropathy
• Cerebellar neoplasms, hemorrhage, abscess, infarct
• Cerebellar and spinocerebellar degeneration: ataxia-telangiectasia, Friedreich’s ataxia
• AIDS

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