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Breast Ulcer
Appearing on the nipple, areola, or the breast itself, an ulcer indicates destruction of the skin and subcutaneous tissue. A breast ulcer is usually a late sign of cancer, appearing well after the confirming diagnosis. Breast ulcers can also result from trauma, infection, or radiation.
History and Physical Examination
Begin the history by asking when the patient first noticed the ulcer and if it was preceded by other breast changes, such as nodules, edema, or nipple discharge, deviation, or retraction. Does the ulcer seem to be getting better or worse? Does it cause pain or produce drainage? Has she noticed any change in breast shape?

Has she had a skin rash? If she has been treating the ulcer at home, find out how. Review the patient’s personal and family history for factors that increase the risk of breast cancer. Ask, for example, about previous cancer, especially of the breast, and mastectomy. Determine whether the patient’s mother or sister has had breast cancer. Ask the patient’s age at menarche and menopause because more than 30 years of menstrual activity increases the risk of breast cancer. Also, ask about pregnancy because nulliparity or birth of a first child after age 30 also
increases the risk of breast cancer.
If the patient recently gave birth, ask if she breast-feeds her infant or has
recently weaned him. Ask if she’s currently taking an oral antibiotic and if she’s diabetic. All these factors predispose the patient to Candida infections.
Inspect the patient’s breast, noting any asymmetry or flattening. Look for a rash, scaling, cracking, or red excoriation on the nipples, areola, and inframammary fold. Check especially for skin changes, such as warmth, erythema, or peau d’orange. Palpate the breast for masses, noting any induration beneath the ulcer. Then, carefully palpate for tenderness or nodules around the areola and the axillary lymph nodes.
Medical Causes
Breast cancer. A breast ulcer that doesn’t heal within a month usually indicates cancer. Ulceration along a mastectomy scar may indicate metastatic cancer; a nodule beneath the ulcer may be a late sign of a fulminating tumor. Other signs include a palpable breast nodule, skin dimpling, nipple retraction, bloody or serous nipple discharge, erythema, peau d’orange, and enlarged axillary lymph nodes.
GENDER CUE
A breast ulcer may be the presenting sign of breast cancer in men, who are more apt to miss or dismiss earlier breast changes. on the nipple, areola, or the breast itself, an ulcer indicates destruction of the skin and subcutaneous tissue. A breast ulcer is usually a late sign of cancer, appearing well after the confirming diagnosis. Breast ulcers can also result from trauma, infection, or radiation.
History and Physical Examination
Begin the history by asking when the patient first noticed the ulcer and if it was preceded by other breast changes, such as nodules, edema, or nipple discharge, deviation, or retraction. Does the ulcer seem to be getting better or worse? Does it cause pain or produce drainage? Has she noticed any change in breast shape?

Has she had a skin rash? If she has been treating the ulcer at home, find out how. Review the patient’s personal and family history for factors that increase the risk of breast cancer. Ask, for example, about previous cancer, especially of the breast, and mastectomy. Determine whether the patient’s mother or sister has had breast cancer. Ask the patient’s age at menarche and menopause because more than 30 years of menstrual activity increases the risk of breast cancer. Also, ask about pregnancy because nulliparity or birth of a first child after age 30 also
increases the risk of breast cancer.
If the patient recently gave birth, ask if she breast-feeds her infant or has
recently weaned him. Ask if she’s currently taking an oral antibiotic and if she’s diabetic. All these factors predispose the patient to Candida infections.
Inspect the patient’s breast, noting any asymmetry or flattening. Look for a rash, scaling, cracking, or red excoriation on the nipples, areola, and inframammary fold. Check especially for skin changes, such as warmth, erythema, or peau d’orange. Palpate the breast for masses, noting any induration beneath the ulcer. Then, carefully palpate for tenderness or nodules around the areola and the axillary lymph nodes.

Differential Diagnosis of Breast Ulcer
Breast cancer. A breast ulcer that doesn’t heal within a month usually indicates cancer. Ulceration along a mastectomy scar may indicate metastatic cancer; a nodule beneath the ulcer may be a late sign of a fulminating tumor. Other signs include a palpable breast nodule, skin dimpling, nipple retraction, bloody or serous nipple discharge, erythema, peau d’orange, and enlarged axillary lymph nodes.

A breast ulcer may be the presenting sign of breast cancer in men, who are more apt to miss or dismiss earlier breast changes.

Breast trauma
Untreated tissue damage leading to insufficient recovery can result in the development of breast ulcers. The associated symptoms vary depending on the nature of the injury but may encompass ecchymosis, lacerations, abrasions, edema, and hematoma.

Candida albicans infection.
If Candida infection is severe, it can lead to maceration of breast tissue followed by ulceration. Distinct, vivid red papular spots, often with scaly edges, distinguish the infection, which may form in the folds of the breast. Fibrous nipples in lactating mothers increase their susceptibility to infection. Mothers characterize the discomfort experienced when the newborn sucks as a piercing ache that extends into the chest wall.

Paget's disease
Excoriation of the bright-red nipple might spread to the areola and give rise to ulcers. Ulceration may be accompanied by profuse or bloody nipple discharge and intense nipple itching. Typically, symptoms manifest unilaterally.

Therapeutic radiation. Post-treatment, the breasts have a "sunburned" appearance. Later on, the skin develops ulcers and the adjacent region becomes erythematous and sensitive.
Special Factors to Consider
When there is suspicion of breast cancer, offer your patient emotional support and motivate her to articulate her emotions. Assess her readiness for diagnostic examinations including ultrasonography, thermography, mammography, nipple discharge cytology, and breast biopsy. Should there be suspicion of a Candida infection, make arrangements for skin or blood cultures.
Therapeutic Counseling for Patients
Educate the patient on the proper application of a topical ointment or cream with antifungal or antibacterial properties. Urge her to maintain dryness of the ulcer to minimize chafing and to don loose-fitting underwear. Elucidate the significance of conducting clinical breast examination and mammography in accordance with the guidelines set forth by the American Cancer Society. Educate the patient on the etiology of the breast ulcer and the subsequent therapeutic strategy following the confirmation of the diagnosis.
References for Geriatrics
Given the heightened susceptibility to breast cancer in this demographic, breast ulcers should be regarded as malignant until scientifically demonstrated otherwise. Nevertheless, ulcers can also arise from typical skin alterations in older individuals, including decreased thickness, reduced blood flow, and diminished flexibility, as well as from inadequate skin care. Pressure ulcers might manifest as a consequence of the use of shackles and tight brassieres, whereas traumatic ulcers may arise after falls or abuse.



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