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Symptoms and Signs – Differential Diagnosis of Guillain-Barré Syndrome
• Acute CNS disorders such as basilar artery thrombosis with brainstem infarction, brainstem encephalomyelitis, transverse myelitis, or spinal cord compression
• Hysterical paralysis or malingering
• Metabolic derangements such as hypermagnesemia, hypokalemia, hypophosphatemia
• Myopathies such as polymyositis, acute necrotizing myopathies caused by drugs
• Neuromuscular junction disorders: myasthenia gravis, botulism, snake envenomations
• Nontoxic peripheral neuropathies: acute intermittent porphyria, vasculitic polyneuropathy, infectious (poliomyelitis, diphtheria, Lyme disease), tick paralysis
• Toxic peripheral neuropathies: heavy metal poisoning (lead, thallium, arsenic), medications (vincristine, disulfiram), organophosphate poisoning, hexacarbon (glue sniffer’s neuropathy)
• Acute CNS disorders such as basilar artery thrombosis with brainstem infarction, brainstem encephalomyelitis, transverse myelitis, or spinal cord compression
• Hysterical paralysis or malingering
• Metabolic derangements such as hypermagnesemia, hypokalemia, hypophosphatemia
• Myopathies such as polymyositis, acute necrotizing myopathies caused by drugs
• Neuromuscular junction disorders: myasthenia gravis, botulism, snake envenomations
• Nontoxic peripheral neuropathies: acute intermittent porphyria, vasculitic polyneuropathy, infectious (poliomyelitis, diphtheria, Lyme disease), tick paralysis
• Toxic peripheral neuropathies: heavy metal poisoning (lead, thallium, arsenic), medications (vincristine, disulfiram), organophosphate poisoning, hexacarbon (glue sniffer’s neuropathy)
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