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Symptoms and Signs – Differential Diagnosis of Hepatomegaly
Cancer: (2° deposits, hepatoma, liver cell adenoma)
Cirrhosis (early) usually alcoholic, primary biliary cirrhosis
Congestive cardiac failure
Budd-Chiari (hepatic vein thrombosis)
Polycystic liver disease
Infection: hepatitis A, B, C, EBV, CMV, toxoplasmosis, leptospirosis, abscess
(amoebic, pyogenic), hydatid cyst
Infiltration: fatty infiltration (alcohol), haemochromatosis, amyloidosis,
sarcoidosis, lymphoproliferative diseases
'Apparent hepatomegaly': lowered diaphragm (e.g. in COPD) or Reidle's lobe (an
extension of the right lobe)
Also see Hepatosplenomegaly


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