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Symptoms and Signs – Differential Diagnosis of Hepatorenal Syndrome
• Acute tubular necrosis: urinary sodium >30, FENa >1.5%, urinary/plasma creatinine ratio <30, urine/plasma osmolality ratio = 1, urine sediment reveals casts and cellular debris; there is no significant response to sustained plasma expansion.
• Prerenal azotemia: response to sustained plasma expansion is good (prompt diuresis with volume expansion).
• Acute tubular necrosis: urinary sodium >30, FENa >1.5%, urinary/plasma creatinine ratio <30, urine/plasma osmolality ratio = 1, urine sediment reveals casts and cellular debris; there is no significant response to sustained plasma expansion.
• Prerenal azotemia: response to sustained plasma expansion is good (prompt diuresis with volume expansion).
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