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Symptoms and Signs – Differential Diagnosis of Hypercoagulable State, Associated Disorders
• Systemic lupus erythematosus in association with the presence of a lupus anticoagulant or antiphospholipid antibodies
• Malignant neoplasm
• Disease related: includes migratory superficial thrombophlebitis (Trousseau’s syndrome), nonbacterial thrombotic endocarditis,thrombosis associated with chronic DIC, thrombotic
microangiopathy
• Treatment related: associated with the administration of various chemotherapeutic agents (asparaginase, mitomycin, someadjuvant chemotherapeutic agents for treatment of breast cancer,thalidomide or lenalidomide in conjunction with high doses of dexamethasone)
• Infusion of prothrombin complex concentrates
• Nephrotic syndrome
• Heparin-induced thrombocytopenia
• Myeloproliferative disorders
• Paroxysmal nocturnal hemoglobinuria
• Systemic lupus erythematosus in association with the presence of a lupus anticoagulant or antiphospholipid antibodies
• Malignant neoplasm
• Disease related: includes migratory superficial thrombophlebitis (Trousseau’s syndrome), nonbacterial thrombotic endocarditis,thrombosis associated with chronic DIC, thrombotic
microangiopathy
• Treatment related: associated with the administration of various chemotherapeutic agents (asparaginase, mitomycin, someadjuvant chemotherapeutic agents for treatment of breast cancer,thalidomide or lenalidomide in conjunction with high doses of dexamethasone)
• Infusion of prothrombin complex concentrates
• Nephrotic syndrome
• Heparin-induced thrombocytopenia
• Myeloproliferative disorders
• Paroxysmal nocturnal hemoglobinuria
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