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Symptoms and Signs – Differential Diagnosis of Immune Thrombocytopenic Purpura
• Congenital thrombocytopenias (e.g., Fanconi’s syndrome, May- Hegglin anomaly, Bernard-Soulier syndrome)
• Drug induced (e.g., heparin, quinidine, sulfonamides)
• Falsely low platelet count (resulting from ethylenediaminetetraacetic acid [EDTA]–dependent or cold dependent agglutinins)
• Hypersplenism resulting from liver disease
• Myelodysplastic and lymphoproliferative disorders
• Pregnancy, hypothyroidism
• Systemic lupus erythematosus (SLE), thrombotic thrombocytopenic purpura (TTP), hemolytic-uremic syndrome (HUS)
• Viral infections (e.g., HIV infection, mononucleosis, rubella)
• Congenital thrombocytopenias (e.g., Fanconi’s syndrome, May- Hegglin anomaly, Bernard-Soulier syndrome)
• Drug induced (e.g., heparin, quinidine, sulfonamides)
• Falsely low platelet count (resulting from ethylenediaminetetraacetic acid [EDTA]–dependent or cold dependent agglutinins)
• Hypersplenism resulting from liver disease
• Myelodysplastic and lymphoproliferative disorders
• Pregnancy, hypothyroidism
• Systemic lupus erythematosus (SLE), thrombotic thrombocytopenic purpura (TTP), hemolytic-uremic syndrome (HUS)
• Viral infections (e.g., HIV infection, mononucleosis, rubella)
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