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Symptoms and Signs – Differential Diagnosis of Ischemic Necrosis of Cartilage and Bone
• Burns
• Collagen-vascular disorders
• Dysbaric conditions (e.g., caisson disease)
• Endocrine/metabolic: ethanol abuse, glucocorticoid therapy, Cushing’s disease, diabetes mellitus (DM), hyperuricemia, osteomalacia, hyperlipidemia, storage diseases (e.g., Gaucher’s disease)
• Hemodialysis
• Hemoglobinopathies (e.g., sickle cell disease)
• HIV infection
• Idiopathic, familial
• Intravascular coagulation
• Irradiation
• Organ transplantation
• Pancreatitis
• Trauma (e.g., dislocation, fracture)
• Burns
• Collagen-vascular disorders
• Dysbaric conditions (e.g., caisson disease)
• Endocrine/metabolic: ethanol abuse, glucocorticoid therapy, Cushing’s disease, diabetes mellitus (DM), hyperuricemia, osteomalacia, hyperlipidemia, storage diseases (e.g., Gaucher’s disease)
• Hemodialysis
• Hemoglobinopathies (e.g., sickle cell disease)
• HIV infection
• Idiopathic, familial
• Intravascular coagulation
• Irradiation
• Organ transplantation
• Pancreatitis
• Trauma (e.g., dislocation, fracture)
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