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Symptoms and Signs – Differential Diagnosis of Ishcemic Cerebrovascular Disease VASCULAR DISORDERS • Large-vessel atherothrombotic disease • Lacunar disease • Arterial-to-arterial embolization • Carotid or vertebral artery dissection • Fibromuscular dysplasia • Migraine • Venous thrombosis • Radiation • Complications of arteriography • Multiple, progressive intracranial arterial occlusions INFLAMMATORY DISORDERS • Giant cell arteritis • Polyarteritis nodosa • Systemic lupus erythematosus (SLE) • Granulomatous angiitis • Takayasu’s disease • Arteritis associated with amphetamine, cocaine, or phenylpropanolamine • Syphilis, mucormycosis • Sjögren’s syndrome • Behçet’s syndrome CARDIAC DISORDERS • Rheumatic heart disease • Mural thrombus • Arrhythmias • Mitral valve prolapse • Prosthetic heart valve • Endocarditis • Myxoma • Paradoxical embolus HEMATOLOGIC DISORDERS • Thrombotic thrombocytopenic purpura • Sickle cell disease • Hypercoagulable states • Polycythemia • Thrombocytosis • Leukocytosis • Lupus anticoagulant 
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