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​Symptoms and Signs – Differential Diagnosis of  Jaundice
PREDOMINANCE OF DIRECT (CONJUGATED) BILIRUBIN
• Extrahepatic obstruction
• Common duct abnormalities: calculi, neoplasm, stricture, cyst, sclerosing cholangitis
• Metastatic carcinoma
• Pancreatic carcinoma, pseudocyst
• Ampullary carcinoma
• Hepatocellular disease: hepatitis, cirrhosis
• Drugs: estrogens, phenothiazines, captopril, methyltestosterone,
Labetalol

PREDOMINANCE OF INDIRECT (UNCONJUGATED)
BILIRUBIN
• Hemolysis: hereditary and acquired hemolytic anemias
• Inefficient marrow production
• Impaired hepatic conjugation: chloramphenicol
• Neonatal jaundice
• Hereditary disorders: Gilbert’s syndrome, Crigler-Najjar syndrome
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Kembara Xtra 

Facts about medicine and its subtopic such as anatomy, physiology, biochemistry, pharmacology, medicine, pediatrics, psychiatry, obstetrics and gynecology and surgery.