- Published on
Symptoms and Signs – Differential Diagnosis of Leg Ulcers
VASCULAR
• Arterial: arteriosclerosis, thromboangiitis obliterans, arteriovenous
(AV) malformation, cholesterol emboli
• Venous: superficial varicosities, incompetent perforators, deep
venous thrombosis (DVT), lymphatic abnormalities
VASCULITIS/HEMATOLOGIC
• Sickle cell anemia, thalassemia, polycythemia vera, leukemia, cold agglutinin disease
• Macroglobulinemia, protein C and protein S deficiency, cryoglobulinemia, lupus anticoagulant, antiphospholipid syndrome
INFECTIOUS
• Fungus: blastomycosis, coccidioidomycosis, histoplasmosis,
sporotrichosis
• Bacterial: furuncle, ecthyma, septic emboli
• Protozoal: leishmaniasis
METABOLIC
• Necrobiosis lipoidica diabeticorum
• Localized bullous pemphigoid
• Gout, calcinosis cutis, Gaucher’s disease
TUMORS
• Basal cell carcinoma, squamous cell carcinoma, melanoma
• Mycosis fungoides, Kaposi’s sarcoma, metastatic neoplasms
TRAUMA
• Burns, cold injury, radiation dermatitis
• Insect bites
• Factitial, excessive pressure
NEUROPATHIC
• Diabetic trophic ulcers
• Tabes dorsalis, syringomyelia
DRUGS
• Warfarin, IV colchicine extravasation, methotrexate, halogens,ergotism, hydroxyurea
PANNICULITIS
• Weber-Christian disease
• Pancreatic fat necrosis, α-antitrypsinase deficiency
VASCULAR
• Arterial: arteriosclerosis, thromboangiitis obliterans, arteriovenous
(AV) malformation, cholesterol emboli
• Venous: superficial varicosities, incompetent perforators, deep
venous thrombosis (DVT), lymphatic abnormalities
VASCULITIS/HEMATOLOGIC
• Sickle cell anemia, thalassemia, polycythemia vera, leukemia, cold agglutinin disease
• Macroglobulinemia, protein C and protein S deficiency, cryoglobulinemia, lupus anticoagulant, antiphospholipid syndrome
INFECTIOUS
• Fungus: blastomycosis, coccidioidomycosis, histoplasmosis,
sporotrichosis
• Bacterial: furuncle, ecthyma, septic emboli
• Protozoal: leishmaniasis
METABOLIC
• Necrobiosis lipoidica diabeticorum
• Localized bullous pemphigoid
• Gout, calcinosis cutis, Gaucher’s disease
TUMORS
• Basal cell carcinoma, squamous cell carcinoma, melanoma
• Mycosis fungoides, Kaposi’s sarcoma, metastatic neoplasms
TRAUMA
• Burns, cold injury, radiation dermatitis
• Insect bites
• Factitial, excessive pressure
NEUROPATHIC
• Diabetic trophic ulcers
• Tabes dorsalis, syringomyelia
DRUGS
• Warfarin, IV colchicine extravasation, methotrexate, halogens,ergotism, hydroxyurea
PANNICULITIS
• Weber-Christian disease
• Pancreatic fat necrosis, α-antitrypsinase deficiency
0 Comments
