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Symptoms and Signs - Differential Diagnosis of Lower Gastrointestinal Bleeding • Volvulus • Vascular abnormalities: angiodysplasia, vascular ectasia • Uremic colitis • Trauma, foreign body • Solitary rectal/cecal ulcers • Small bowel neoplasm: leiomyomas, carcinoids • Polyarteritis nodosa • Other: pancreaticoenteric fistulas, Henoch-Schönlein purpura, Ehlers-Danlos syndrome, systemic lupus erythematosus (SLE), amyloidosis, metastatic melanoma • Meckel’s diverticulum and other small intestine diverticula • Lymphoma of small bowel, sarcoma, Kaposi’s sarcoma • Lymphoma of large bowel • Long-distance running • Ischemic colitis • Ischemic bowel disease (mesenteric thrombosis, embolism, vasculitis, trauma) • Irradiation ileitis • Irradiation colitis • Intussusception • Intestinal hemangiomas: blue rubber bleb nevi, intestinal hemangiomas, cutaneous vascular nevi • Inflammatory bowel disease (IBD) • Infectious colitis • Infections of small bowel: tuberculous enteritis, enteritis necroticans • Hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome) • Hemorrhoids • Hamartomatous polyps: Peutz-Jeghers syndrome (intestinal polyps, mucocutaneous pigmentation) • Diverticular disease • Colonic polyps • Carcinoma (particularly left colon) • AV malformation of small intestine • Aortoenteric fistula • Anal fissure 
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