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Symptoms and Signs – Differential Diagnosis of Microcytic Anaemia
Anaemia of chronic disease (often normocytic, but may be microcytic)
Iron deficiency: blood loss (GI [e.g. peptic ulcer, malignancy), urogenital [e.g. menorrhagia, haematuria)), hookworm (Ancylostroma duodenale)
Lead poisoning
Reduced absorption (gastrectomy, small bowel disease),increased demands (growth, pregnancy), reduced intake (e.g. vegans)
Sideroblastic anaemia: congenital (X-linked), alcohol, drugs (isoniazid, chloramphenicol), lead, myelodysplasia
Thalassaemia
Anaemia of chronic disease (often normocytic, but may be microcytic)
Iron deficiency: blood loss (GI [e.g. peptic ulcer, malignancy), urogenital [e.g. menorrhagia, haematuria)), hookworm (Ancylostroma duodenale)
Lead poisoning
Reduced absorption (gastrectomy, small bowel disease),increased demands (growth, pregnancy), reduced intake (e.g. vegans)
Sideroblastic anaemia: congenital (X-linked), alcohol, drugs (isoniazid, chloramphenicol), lead, myelodysplasia
Thalassaemia
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